VUS Program
Support for families told they carry a "variant of uncertain significance" in RNU4-2 or RNU6.
About the VUS program
A variant of uncertain significance (VUS) is a genetic change that has been found but not yet confirmed to cause disease. For families, a VUS result can be one of the most confusing and frustrating outcomes of genetic testing — neither a clear answer nor a clear all-clear.
Because RNU4-2 and RNU6 retinal disease was only recently discovered, many variants in these genes are still being classified. The CURE4/6 VUS program aims to help affected families and their clinicians make sense of these results and contribute to the research that reclassifies them.
You can register your interest below and we will be in touch as the program develops.